Endocrine Abstracts

Introduction: The prevalence of thyroid diseases increase with age. Mostly, they are undiagnosed. The lack of overt clinical appearance of hypo-hyperthyroidism in elder people increases the need for an attentive clinician to suspect and investigate for their presence. Thyroid dysfunctions, especially subclinics, are more frequently seen in older populations, have been linked to increased morbidity and mortality. Therefore, elderly people should evaluate in terms of thyroid fun...

Aim: Hashimoto’s thyroiditis (HT) is the commonest autoimmune thyroid disease. Papillary thyroid cancer (PTC) is the most often thyroid cancer and its incidence is increasing yearly. It is not clear that HT is a predisposing factor for PTC. We studied PTC’s frequency among HT patients went to total thyroidectomy.Materials and methods: Five hundred and thirty four patients done total thyroidectomy by general surgery were evaluated retrospectivel...

Objective: Vitamin D is an immune-modulator that may play a role in thyroid related autoimmunity. But the relation between Vitamin D and Graves’ disease (GD) is not well defined yet. The aim of this study was to investigate the association of 25-hydroxy-vitamin D (25[OH]D) levels and TSH receptor antibody (TRab) levels in GD.Design: A total of 429 GD patients were analyzed retrospectively. 122 of 429 patients had vitamin D levels were enrolled in th...

Objective: Currently there are three well-established treatment options for hyperthyroid Graves’ disease (GD): antithyroid drug therapy with thionamides, radioactive iodine (RAI) treatment with (131)I, and surgery. The aim of this study was to investigate retrospectively theurapeutic options of the patients with GD treated at outpatient clinics of Endocrinology and Metabolism between January 2007 and December 2009.Methods: We evaluated 122 patients ...

Aim: Thyroid hormones have many effects on the cardiovascular system. May studies have showed that apparent or subclinical hypothyroidism increase the risk of hypertension hyperlipidemia and so lead to atherosclerosis susceptibility. This risk can be reduced by treatment. But, studies on the relationship between thyroid function tests and cardiovascular risk in euthyroid subjects are contradictory. This study was designed to investigate the effect of TSH, free T3, f...

Introduction: Bariatric surgery would end up with great alterations in homeostatic measures such as glucose and lipid metabolism and hormonal regulation, which of all are interweaved with some number of ways to each other. The hormonal modulation extands along a wide span starting from the change in gastrointestinal peptides, to the effect in insulin and other nutrient metabolism regulatory hormones and even the hormones establishing thyroid and calcium homeostasis. Secondary ...

Introduction: Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumor type. They are usually recognized after they cause symptoms especially when tumor size increases and eventually invades adjacent structures. Nevertheless the discovery would also be accidental. In the literature some kind of gender difference is reported in NFA’s behavioral results such as pituitary axis deficits or consequences of surgery however they resulted with contr...

Aim: There are studies showing that Hashimoto’s thyroiditis (HT) progresses more rapidly, thyroid echogenicity is lower and thyroid autoantibodies are higher titer positive in immunoglobulin G4 (IGg4) positive patients.But a small number of studies that do not support this data have also been published.We planned this study to evaluate the findings of IgG4 (+) Hashimoto’s thyroiditis cases.Materials and methods: New diagnosis without treatment ...

Introduction: Autoimmune polyglandular syndrome type 2 (APS2) is the most common form of the polyglandular failure syndromes. Seventy-five percent of cases occur in women. Adrenal insufficiency is the principal manifestation occurs with autoimmune thyroid disease or type I diabetes mellitus. The incidence of autoimmune thyroid diseases in APS2 is 70%; 30% Hashimoto’s thyroiditis, 20% non toxic goiter, 20% hypertyroidism is seen. We will discuss about a patient with APS2, ...

Aims: We aimed to determine the irisin level in patients with type 1 diabetes mellitus (T1DM) and to examine the relation of irisin level with inflammation and autoimmunity.Methods: This study included 35 cases diagnosed with T1DM and 36 healthy volunteers. Anti-glutamic acid decarboxylase (Anti-GAD), islet cell antibody (ICA), insulin autoantibody levels of the patients have been measured at the time they were included in the study and were recorded fro...